.CRAM File Extension

File Type:
Compressed Alignment File

Having trouble opening .cram extension? Don't panic! This page explains what cram files are as well as suggests programs you may use to open cram files. You can download these programs through this page.

What is a CRAM file?

Cram file extension has Compressed Alignment file type, developed by EBI, which is associated with the "data files" category.

These are files in the compressed format, which was designed to save short DNA sequences read alignments received from short read aligners. The CRAM format is similar to the BAM format (Binary Alignment/Map) but has better compression rate and a different structure of the column-oriented binary container format. This format allows reducing the space needed to save data volumes generated by the genetic software.

To learn how you can open the given file, read the information below.

cram file icon
File Type:
Compressed Alignment File
Data Files

How to open CRAM file?

Double click the cram file to open it. The file will open automatically if file associations have been correctly installed and there is a proper program on your computer; if not, file associations may be corrupted and your OS either cannot find the proper program, or you might not have one for opening the file. First, we recommend downloading our utility to fix file association errors; then, you can download any program for opening the .cram extension from the ones suggested below. If you are certain there is nothing wrong with the file associations, you may proceed to method 2 right away; besides, if you can't make up your mind when choosing the right program, use Universal File Viewer from the last method.

Method 1: Fix file association errors

Follow these steps in order to automatically fix the cram extension associations' problem in no time:

  • Step 1: Click on "Download Solution" to download automatic tool provided by WikiExt.
  • Step 2: Click "Start Scan" to identify all potential issues.
  • Step 3: Review scan results and click "Fix Items".

File Size: 3.04 MB, Download time: < 1 min. on DSL/ADSL/Cable

This Tool is Compatible With: Windows XP, Vista, 7, 8/8.1, 10

Method 2: Download the appropriate software

The given list provides programs which may be used for opening or converting the cram file. Choose the proper program for your OS, and click it to start the download or proceed to the developer's website.

Programs that open CRAM files

Method 3: Use universal file viewer

In addition to the list of programs above, we recommend using Universal File Viewer. This tool can open over 250 file extensions and, most likely, it will be able to open the cram file as well. Download Universal File Viewer for your OS.

Download for Win
Secure download
Download for Mac
Secure download